Investigation of serum leptin, thyroid hormones and some biochemical parameters in sarcoptic sheep: a preliminary study

  • Ozkan Duru Kırıkkale Üniversitesi
  • Ali Şenol
  • Alparslan Kadir Devrim
  • Sibel Yasa Duru
  • Yasin Parlatir
Keywords: Sarcoptic sheep, thyroid hormone, biochemical parameters, leptin.


The aim of this study was to determine the effects of the parasitic infestation on some hormonal and biochemical values ​​in sheep infected with sarcoptic scabies. In this context, leptin and thyroid hormones which are important in metabolism and some biochemical changes were examined. The study material was selected from sheeps presented to Research and Application Hospital of Veterinary Faculty of Kırıkkale University and divided into two groups. The first group was consisted of sheeps infected with sarcoptic scabies and the second group was selected from healthy sheeps. The blood samples were collected from vena jugularis to serum tubes and they were centrifugated for the separation of the sera. The biochemical measurements were performed on these serum samples to investigate the levels of T3, T4, FT3, FT4 and leptin hormones as well as magnesium, albumin, total protein, uric acid, inorganic phosphate, triglyceride, calcium, creatine kinase and cholesterol. From these parameters, T4, calcium and cholesterol were increased and the FT3 values were decreased in the group of sarcoptic sheeps (p<0.05). Our data suggest that sarcoptic scabies may disturb the balance of thyroid hormone levels and lead to differences in the levels of biochemical parameters.